Dra. Crespo

Dra. Magdalena Guerra Crespo
mguerra@ifc.unam.mx, magdagmx@hotmail.com
Investigador Titular “A” TC
Titular del laboratorio de Medicina Regenerativa
Departamento de Fisiología
Facultad de Medicina
Universidad Nacional Autónoma de México (UNAM)


  1. Boronat-García A, Palomero-Rivero M, Guerra-Crespo M. Adrenal grafts in the central nervous system: Chromaffin and chromaffin progenitor cell transplantation. 2023. Methods in Molecular Biology, Chromaffin Cells Vol. 2565 pp, [SpringerNature].

  2. Ramos-Acevedo R, Morato-Torres CA, Francisco J. Padilla-Godínez, Bernal-Conde LD, Palomero-Rivero M, Faria Zafar, Luis Oskar Soto-Rojas, Schüle B, Guerra-Crespo M. 2023. Embryoid body cells from human embryonic stem cells overexpressing dopaminergic transcription factors survive and initiate neurogenesis via neural rosettes in the substantia nigra. Brain Sciences. 13(2):329.

  3. Pérez Segura Isaac, Santiago-Balmaseda Alberto, Rodríguez-Hernández Luis Daniel, Morales-Martínez Adriana, Martínez-Becerril Hilda Angélica, Martínez-Gómez Paola A., Delgado-Minjares Karen M., Salinas-Lara Citlaltepetl, Martínez-Dávila Irma A., Guerra-Crespo Magdalena, Pérez-Severiano Francisca, Soto-Rojas Luis O. 2023. PPARs and their neuroprotective effects in Parkinson´s disease: a novel therapeutic approach in α-synucleinopathy? International Journal of Molecular Sciences. 24(4):3264.

  4. Guerra-Crespo M, Collazo-Navarrete O, Ramos-Acevedo R, Morato-Torres CA, Schüle B. 2022. Embryoid body formation from mouse and human pluripotent stem cells for transplantation to study brain microenvironment and cellular differentiation. Methods in Molecular Biology, Embryonic Stem Cell Protocols Volume 2520 pp 215-232 [SpringerNature].

  5. Padilla-Godínez Francisco J, Ruiz-Ortega Leonardo I, Guerra-Crespo Magdalena. Nanomedicine in the Face of Parkinsons Disease: From Drug Delivery Systems to Nanozymes. 2022. Cells. 11(21):3445.

  6. Padilla-Godínez FJ, Ramos-Acevedo R, Martínez-Becerril HA, Bernal-Conde LD, Garrido-Figueroa JF, Hiriart M, Hernández-López A, Argüero-Sánchez R, Callea F, Guerra-Crespo M. 2021. Protein Misfolding and Aggregation: The Relatedness between Parkinson’s Disease and Hepatic Endoplasmic Reticulum Storage Disorders. 2021. International Journal of Molecular Sciences. 22(22):12467.

  7. Bernal-Conde LD, Ramos-Acevedo R, Reyes-Hernández MA, Balbuena-Olvera A, Morales-Moreno ID, Argüero-Sánchez R, Schüle B, Guerra-Crespo M. 2020. Alpha-synuclein physiology and pathology: A perspective on cellular structures and organelles. Frontiers in Neurosciences. 13:1399.

  8. Collazo-Navarrete O, Hernández-García D, Guerrero-Flores G, Drucker-Colín R, Guerra-Crespo M, Covarrubias L. 2019. The substantia nigra is permissive and gains inductive signals when lesioned for dopaminergic differentiation of embryonic stem cells. Stem Cells and Development. 28(16):1104-1115.

  9. Arzate-Vázquez DM, Guerra-Crespo M and Covarrubias L. 2019. Induction of typical and atypical neurogenesis in the adult substantia nigra after mouse embryonic stem cells transplantation. Neuroscience. 408: 308-326.

  10. Guerrero-Flores G, Bastidas-Ponce A, Collazo-Navarrete O, Guerra-Crespo M and Covarrubias L. 2017. Functional determination of the differentiation potential of ventral mesencephalic neural precursor cells during dopaminergic neurogenesis. Developmental Biology. 429(1):56-70.

  11. Boronat-García A, Guerra-Crespo M, Drucker-Colín R. 2017. A Historical Perspective of Cell Transplantation in Parkinson’s disease. World Journal of Transplantation. 7(3):179-192.

  12. Boronat-García A, Palomero-Rivero M, Guerra-Crespo M, Millán-Aldaco D, Drucker-Colín R. 2016. Intrastriatal Grafting of Chromospheres: Survival and Functional Effects in the 6-OHDA Rat Model of Parkinson´s Disease. PLoS One. 15;11(8):e0160854.

  13. Trujillo-Paredes N, Valencia C, Guerrero-Flores G. Arzate-DM. Baizabal JM, Guerra-Crespo M, Fuentes-Hernández A, Zea-Armenta I and Covarrubias-Robles L. 2016. Regulation of differentiation flux by Notch signalling influences the number of dopaminergic neurons in the adult brain. Biology Open. 5(3):336-47.

  14. Maya-Espinosa G, Collazo-Navarrete O, Millán-Aldaco D, Palomero-Rivero M, Guerrero-Flores G, Drucker-Colín R, Covarrubias L and Guerra-Crespo M. 2015. Mouse embryonic stem cell-derived cells reveal niches that support neuronal differentiation in the adult rat brain. Stem Cells. 33(2):491-502.

  15. García-Montes J.R., Boronat García A., López-Colomé A.M., Bargas-Díaz J., Guerra-Crespo M. and Drucker-Colín R. 2012. Is nicotine protective against Parkinson´s Disease?: An experimental analysis. CNS & Neurological Disorders-Drug Targets. 11(7):897-906.

  16. De la Herrán-Arita A. K., Guerra-Crespo M., Drucker-Colín R. 2011. Narcolepsy and Orexins: an example of progress in sleep research. Frontiers in Neurology. 26:1-8.

  17. De la Herrán-Arita A. K., Zomosa-Signoret V.C., Millán-Aldaco D. A., Palomero- Rivero M., Guerra-Crespo M., Drucker-Colín R and Vidaltamayo R. 2011. Aspects of the Narcolepsy-Cataplexy syndrome in O/E3 (Ebf2)-null mutant mice. Neuroscience. 183:134-143.

  18. Guerra-Crespo, M., Pérez-Monter C., Chandra Janga S., Gutiérrez-Rios RM., Castillo-Ramírez S., Joseph-Bravo, P., Pérez-Martínez, L., and Charli, J. L., 2011. Transcriptional profiling of fetal hypothalamic TRH neurons. BMC Genomics. 12, 222.

  19. .Guerra-Crespo, M., Sistos, A., Gleason, D. and Fallon J.H. 2010. Intranasal Administration of PEGylated TGF-alpha Improves Behavioral Deficits in a Chronic Stroke Model. Journal of Stroke and Cerebrovascular diseases. 19:3-9. Autor responsable.

  20. Guerra-Crespo, M., Gleason, D., Sistos, A., Zhang J.H., Solaroglu I., Bryant P.J., Fallon J.H. 2009. Transforming Growth Factor-alpha Induces Neurogenesis and Behavioral Improvement in a Chronic Stroke Model. Neuroscience 160:470-483. Autor responsable.

  21. Gleason, D. Fallon J.H., Guerra M., Liu J.C. and Bryant P.J. 2008. Ependymal stem cells divide asymmetrically and transfer progeny into the subventricular zone when activated by injury. Neuroscience. 156:81-88.

  22. Guerra Crespo, M., Charli, J. L., Rosales García V. H., Pedraza-Alva, G., and Pérez- Martínez, L. 2003. Polyethylenimine improves the transfection efficiency of primary cultures of post-mitotic rat fetal hypothalamic neurons. Journal of Neuroscience Methods. 127:179-192.

  23. Guerra-Crespo, M., Ubieta, R., Joseph-Bravo, P., Charli, J. L. and Pérez-Martínez, L. 2001. BDNF increases the early expression of TRH mRNA in fetal TrKB+ hypothalamic neurons in primary culture. European Journal of Neuroscience. 14: 483-494.

  24. Niquet, J., Pérez-Martínez, L., Guerra-Crespo, M., Grouselle, D., Joseph-Bravo, P. and Charli, J. L. 2000. Extracellular matrix proteins increase the expression of pro-TRH and pro-protein convertase PC1 in fetal hypothalamic neurons in vitro. Developmental Brain Research. 120:49-56.


Página oficial Dra. Magdalena Guerra Crespo. Última actualización: Enero 2024.